About Albendazole (MEDZOLE) 400mg Tablet 100’s

Albendazole (MEDZOLE) 400mg Tablet is a broad-spectrum anthelmintic (anti-worm medication) used to treat a variety of parasitic worm infestations in both adults and children. Each tablet contains 400mg of albendazole, a synthetic benzimidazole derivative that works by inhibiting the microtubule synthesis in intestinal parasites, leading to impaired glucose uptake and eventual parasite death.

This medication is highly effective against a wide range of intestinal and tissue parasites, making it a cornerstone treatment in deworming campaigns and clinical settings. It is commonly used in the management of intestinal helminth infections such as ascariasis (roundworm), enterobiasis (pinworm), trichuriasis (whipworm), and hookworm infections, as well as tissue parasites like cysticercosis and hydatid disease.

Albendazole (MEDZOLE) 400mg Tablet is available in a convenient pack of 100 tablets, making it suitable for both individual use and mass treatment programs in community and healthcare settings. It is usually administered as a single-dose therapy but can also be given in longer courses depending on the type and severity of the parasitic infection.

Indications of Albendazole (MEDZOLE) 400mg Tablet 100’s

Albendazole (MEDZOLE) 400mg Tablet is indicated for the treatment of the following parasitic infections:

• Ascariasis (roundworm)

• Enterobiasis (pinworm)

• Trichuriasis (whipworm)

• Ancylostomiasis (hookworm)

• Strongyloidiasis

• Taeniasis (tapeworm)

• Neurocysticercosis caused by Taenia solium

• Hydatid disease (echinococcosis) caused by Echinococcus granulosus

• Giardiasis (in children)

Albendazole is also used as a preventive deworming agent in endemic regions and is part of public health deworming programs recommended by the World Health Organization (WHO).

Dosage and Administration of Albendazole (MEDZOLE) 400mg Tablet 100’s

The dosage may vary depending on the patient’s age, weight, and specific parasitic infection. Always follow healthcare professional instructions. General guidelines include:

• For common intestinal helminths (e.g., roundworm, pinworm, hookworm, whipworm):

  • Adults and children over 2 years: 400mg as a single dose.

  • Children 1-2 years: 200mg as a single dose.

• For neurocysticercosis:

  • 15 mg/kg/day in two divided doses for 8–30 days.

• For hydatid disease:

  • 10–15 mg/kg/day in two divided doses for 28-day cycles with a 14-day drug-free interval. May require up to 3 cycles.

• For strongyloidiasis and taeniasis:

  • 400mg once daily for 3 consecutive days.

Albendazole tablets can be taken with or without food, but taking it with a fatty meal may enhance absorption.

Contraindications of Albendazole (MEDZOLE) 400mg Tablet 100’s

• Known hypersensitivity to albendazole or any benzimidazole derivatives.

• Pregnancy, especially in the first trimester—use is contraindicated due to potential teratogenicity.

• Severe hepatic impairment: caution is advised, and liver function monitoring may be necessary.

• Children under 1 year of age: safety and efficacy not well established for all indications.

Side Effects of Albendazole (MEDZOLE) 400mg Tablet 100’s

Common side effects may include:

• Nausea

• Vomiting

• Abdominal pain

• Dizziness

• Headache

• Temporary hair loss

Less common but serious effects include:

• Elevated liver enzymes

• Bone marrow suppression (rare)

• Allergic reactions such as rash or urticaria

Precautions for Albendazole (MEDZOLE) 400mg Tablet 100’s

• Perform liver function tests and complete blood count (CBC) in long-term therapy (e.g., for cysticercosis or hydatid disease).

• Avoid pregnancy during and for at least one month after treatment.

• Use with caution in patients with liver disease.

• Neurocysticercosis patients should be co-administered corticosteroids and anticonvulsants to manage inflammation-related side effects.

Storage of Albendazole (MEDZOLE) 400mg Tablet 100’s

• Store in a cool, dry place below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.